Driving Independent Pharmacy Profitability in 2026 with Nicolette Mathey, PharmD, CEO of Atrium24

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Peptides, telemedicine, speed-to-market. Independent pharmacies have real profitability levers in 2026 but the winners will be the ones who can move fast and stay compliant.

In this episode, Scotty Sykes, CPA, CFP, Bonnie Bond, CPA, MBA, and Austin Murray sit down with Dr. Nicolette Mathey, PharmD, CEO of Atrium24 to unpack what’s changing right now in the compounding and wellness economy.

We cover:

• Why peptides are exploding in demand
• What to know about BPC-157 and why many think FDA movement could be coming
• How pharmacies can use telemedicine to keep patients from being captured by big direct-to-consumer platforms
• Where compounding pharmacies are still thriving
• Speed to market without reckless risk

More About Our Guest:

Dr. Nicolette Mathey started her career at Walgreens at age 16 and earned her PharmD from the University of Florida in 2010. After pioneering a successful Bedside Delivery program at BayCare Health Systems, she became the Director of Clinical Services at Pharmacy Development Services. There, she co-developed the Clinical Services Profit Ignitor and played a pivotal role in early data analytics.

In 2017, Nicolette acquired Palm Harbor Pharmacy, transforming it from a contracts-only establishment in a Heat Zone to a thriving hub. She revamped its identity, introducing robust digital marketing, a multi-rep sales system, compounding, immunizations, NABP accreditation, Test & Treat, Pharmacogenomic (PGX) Testing, and more.

In 2019, Nicolette founded ATRIUM24, initially offering business consulting to pharmacies. Focused on developing software to automate data analytics and launch Dotti, the industry’s first CRM sales system tailored for pharmacies, she sold Palm Harbor Pharmacy to another independent owner in October 2023.

With the official launch of Dotti in January 2024, Dr. Mathey continues to innovate, aiding pharmacies in maximizing their data for profitability and growth. Through ATRIUM24 and Dotti, she and her team “connect the dots” for sales and marketing initiatives, empowering pharmacies with cutting-edge tools.

Stay connected with Nicolette, Atrium24, and Dotti:

Nicolette’s LinkedIn

Atrium24 Website

Atrium24 Facebook

Atrium24 LinkedIn

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More resources on this topic:

Podcast – The Startup Compounding Pharmacy Playbook

Podcast – Inside the Fight for Compounding: Advocacy, Growth, and Regulation